WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=30; E=8.65; R=3.47; rawP=1.53e-09; adjP=4.54e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143376 NA SNX27 sorting nexin family member 27 81609 ENSG00000143376
2  ENSG00000125122 NA LRRC29 leucine rich repeat containing 29 26231 ENSG00000125122
3  ENSG00000205323 NA SARNP SAP domain containing ribonucleoprotein 84324 ENSG00000205323
4  ENSG00000165526 NA RPUSD4 RNA pseudouridylate synthase domain containing 4 84881 ENSG00000165526
5  ENSG00000163006 NA CCDC138 coiled-coil domain containing 138 165055 ENSG00000163006
6  ENSG00000102401 NA ARMCX3 armadillo repeat containing, X-linked 3 51566 ENSG00000102401
7  ENSG00000198793 NA MTOR mechanistic target of rapamycin (serine/threonine kinase) 2475 ENSG00000198793
8  ENSG00000130956 NA HABP4 hyaluronan binding protein 4 22927 ENSG00000130956
9  ENSG00000158161 NA EYA3 eyes absent homolog 3 (Drosophila) 2140 ENSG00000158161
10  ENSG00000119487 NA MAPKAP1 mitogen-activated protein kinase associated protein 1 79109 ENSG00000119487
11  ENSG00000129250 NA KIF1C kinesin family member 1C 10749 ENSG00000129250
12  ENSG00000101266 NA CSNK2A1 casein kinase 2, alpha 1 polypeptide 1457 ENSG00000101266
13  ENSG00000105953 NA OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 4967 ENSG00000105953
14  ENSG00000099968 NA BCL2L13 BCL2-like 13 (apoptosis facilitator) 23786 ENSG00000099968
15  ENSG00000158560 NA DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1780 ENSG00000158560
16  ENSG00000179889 NA PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 23042 ENSG00000179889
17  ENSG00000126777 NA KTN1 kinectin 1 (kinesin receptor) 3895 ENSG00000126777
18  ENSG00000070182 NA SPTB spectrin, beta, erythrocytic 6710 ENSG00000070182
19  ENSG00000123240 NA OPTN optineurin 10133 ENSG00000123240
20  ENSG00000115677 NA HDLBP high density lipoprotein binding protein 3069 ENSG00000115677
21  ENSG00000173692 NA PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 5707 ENSG00000173692
22  ENSG00000108861 NA DUSP3 dual specificity phosphatase 3 1845 ENSG00000108861
23  ENSG00000181852 NA RNF41 ring finger protein 41 10193 ENSG00000181852
24  ENSG00000119318 NA RAD23B RAD23 homolog B (S. cerevisiae) 5887 ENSG00000119318
25  ENSG00000146872 NA TLK2 tousled-like kinase 2 11011 ENSG00000146872
26  ENSG00000109689 NA STIM2 stromal interaction molecule 2 57620 ENSG00000109689
27  ENSG00000035403 NA VCL vinculin 7414 ENSG00000035403
28  ENSG00000166167 NA BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 8945 ENSG00000166167
29  ENSG00000108424 NA KPNB1 karyopherin (importin) beta 1 3837 ENSG00000108424
30  ENSG00000164068 NA RNF123 ring finger protein 123 63891 ENSG00000164068


Database:Transcription Target       Name:hsa_AACTTT_UNKNOWN       ID:DB_ID:1851
C=1859; O=19; E=5.56; R=3.42; rawP=2.90e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143376 NA SNX27 sorting nexin family member 27 81609 ENSG00000143376
2  ENSG00000102401 NA ARMCX3 armadillo repeat containing, X-linked 3 51566 ENSG00000102401
3  ENSG00000017797 NA RALBP1 ralA binding protein 1 10928 ENSG00000017797
4  ENSG00000033050 NA ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 10061 ENSG00000033050
5  ENSG00000138798 NA EGF epidermal growth factor 1950 ENSG00000138798
6  ENSG00000109685 NA WHSC1 Wolf-Hirschhorn syndrome candidate 1 7468 ENSG00000109685
7  ENSG00000196821 NA C6orf106 chromosome 6 open reading frame 106 64771 ENSG00000196821
8  ENSG00000101266 NA CSNK2A1 casein kinase 2, alpha 1 polypeptide 1457 ENSG00000101266
9  ENSG00000184602 NA SNN stannin 8303 ENSG00000184602
10  ENSG00000158560 NA DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1780 ENSG00000158560
11  ENSG00000176407 NA KCMF1 potassium channel modulatory factor 1 56888 ENSG00000176407
12  ENSG00000070182 NA SPTB spectrin, beta, erythrocytic 6710 ENSG00000070182
13  ENSG00000116199 NA FAM20B family with sequence similarity 20, member B 9917 ENSG00000116199
14  ENSG00000133424 NA LARGE like-glycosyltransferase 9215 ENSG00000133424
15  ENSG00000146872 NA TLK2 tousled-like kinase 2 11011 ENSG00000146872
16  ENSG00000198648 NA STK39 serine threonine kinase 39 27347 ENSG00000198648
17  ENSG00000035403 NA VCL vinculin 7414 ENSG00000035403
18  ENSG00000166167 NA BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 8945 ENSG00000166167
19  ENSG00000025800 NA KPNA6 karyopherin alpha 6 (importin alpha 7) 23633 ENSG00000025800


Database:Transcription Target       Name:hsa_V$PPARA_02       ID:DB_ID:2161
C=127; O=6; E=0.38; R=15.79; rawP=2.45e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000129250 NA KIF1C kinesin family member 1C 10749 ENSG00000129250
2  ENSG00000198952 NA SMG5 smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 23381 ENSG00000198952
3  ENSG00000100380 NA ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 6767 ENSG00000100380
4  ENSG00000108424 NA KPNB1 karyopherin (importin) beta 1 3837 ENSG00000108424
5  ENSG00000119318 NA RAD23B RAD23 homolog B (S. cerevisiae) 5887 ENSG00000119318
6  ENSG00000204843 NA DCTN1 dynactin 1 1639 ENSG00000204843


Database:Transcription Target       Name:hsa_TGGNNNNNNKCCAR_UNKNOWN       ID:DB_ID:2368
C=411; O=9; E=1.23; R=7.32; rawP=4.45e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115677 NA HDLBP high density lipoprotein binding protein 3069 ENSG00000115677
2  ENSG00000108861 NA DUSP3 dual specificity phosphatase 3 1845 ENSG00000108861
3  ENSG00000197798 NA FAM118B family with sequence similarity 118, member B 79607 ENSG00000197798
4  ENSG00000183576 NA SETD3 SET domain containing 3 84193 ENSG00000183576
5  ENSG00000012232 NA EXTL3 exostoses (multiple)-like 3 2137 ENSG00000012232
6  ENSG00000158161 NA EYA3 eyes absent homolog 3 (Drosophila) 2140 ENSG00000158161
7  ENSG00000035403 NA VCL vinculin 7414 ENSG00000035403
8  ENSG00000070182 NA SPTB spectrin, beta, erythrocytic 6710 ENSG00000070182
9  ENSG00000188549 NA C15orf52 chromosome 15 open reading frame 52 388115 ENSG00000188549


Database:Transcription Target       Name:hsa_TMTCGCGANR_UNKNOWN       ID:DB_ID:2370
C=158; O=6; E=0.47; R=12.70; rawP=8.62e-06; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116698 NA SMG7 smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) 9887 ENSG00000116698
2  ENSG00000146872 NA TLK2 tousled-like kinase 2 11011 ENSG00000146872
3  ENSG00000009307 NA CSDE1 cold shock domain containing E1, RNA-binding 7812 ENSG00000009307
4  ENSG00000167721 NA TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 55720 ENSG00000167721
5  ENSG00000198952 NA SMG5 smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 23381 ENSG00000198952
6  ENSG00000114956 NA DGUOK deoxyguanosine kinase 1716 ENSG00000114956


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=21; E=7.33; R=2.87; rawP=1.25e-05; adjP=0.0006
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000205323 NA SARNP SAP domain containing ribonucleoprotein 84324 ENSG00000205323
2  ENSG00000165526 NA RPUSD4 RNA pseudouridylate synthase domain containing 4 84881 ENSG00000165526
3  ENSG00000102401 NA ARMCX3 armadillo repeat containing, X-linked 3 51566 ENSG00000102401
4  ENSG00000012232 NA EXTL3 exostoses (multiple)-like 3 2137 ENSG00000012232
5  ENSG00000158161 NA EYA3 eyes absent homolog 3 (Drosophila) 2140 ENSG00000158161
6  ENSG00000138798 NA EGF epidermal growth factor 1950 ENSG00000138798
7  ENSG00000155984 NA TMEM185A transmembrane protein 185A 84548 ENSG00000155984
8  ENSG00000129250 NA KIF1C kinesin family member 1C 10749 ENSG00000129250
9  ENSG00000073792 NA IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 10644 ENSG00000073792
10  ENSG00000164091 NA WDR82 WD repeat domain 82 80335 ENSG00000164091
11  ENSG00000111540 NA RAB5B RAB5B, member RAS oncogene family 5869 ENSG00000111540
12  ENSG00000126777 NA KTN1 kinectin 1 (kinesin receptor) 3895 ENSG00000126777
13  ENSG00000070182 NA SPTB spectrin, beta, erythrocytic 6710 ENSG00000070182
14  ENSG00000115677 NA HDLBP high density lipoprotein binding protein 3069 ENSG00000115677
15  ENSG00000173960 NA UBXN2A UBX domain protein 2A 165324 ENSG00000173960
16  ENSG00000165675 NA ENOX2 ecto-NOX disulfide-thiol exchanger 2 10495 ENSG00000165675
17  ENSG00000108861 NA DUSP3 dual specificity phosphatase 3 1845 ENSG00000108861
18  ENSG00000132613 NA MTSS1L metastasis suppressor 1-like 92154 ENSG00000132613
19  ENSG00000146872 NA TLK2 tousled-like kinase 2 11011 ENSG00000146872
20  ENSG00000188549 NA C15orf52 chromosome 15 open reading frame 52 388115 ENSG00000188549
21  ENSG00000204843 NA DCTN1 dynactin 1 1639 ENSG00000204843


Database:Transcription Target       Name:hsa_V$ATF_01       ID:DB_ID:1856
C=256; O=6; E=0.77; R=7.84; rawP=0.0001; adjP=0.0021
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115677 NA HDLBP high density lipoprotein binding protein 3069 ENSG00000115677
2  ENSG00000105953 NA OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 4967 ENSG00000105953
3  ENSG00000100380 NA ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 6767 ENSG00000100380
4  ENSG00000179889 NA PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 23042 ENSG00000179889
5  ENSG00000140632 NA GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 84656 ENSG00000140632
6  ENSG00000204843 NA DCTN1 dynactin 1 1639 ENSG00000204843


Database:Transcription Target       Name:hsa_TGACCTY_V$ERR1_Q2       ID:DB_ID:2414
C=1023; O=12; E=3.06; R=3.92; rawP=6.14e-05; adjP=0.0021
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108861 NA DUSP3 dual specificity phosphatase 3 1845 ENSG00000108861
2  ENSG00000154917 NA RAB6B RAB6B, member RAS oncogene family 51560 ENSG00000154917
3  ENSG00000064393 NA HIPK2 homeodomain interacting protein kinase 2 28996 ENSG00000064393
4  ENSG00000101266 NA CSNK2A1 casein kinase 2, alpha 1 polypeptide 1457 ENSG00000101266
5  ENSG00000129250 NA KIF1C kinesin family member 1C 10749 ENSG00000129250
6  ENSG00000196821 NA C6orf106 chromosome 6 open reading frame 106 64771 ENSG00000196821
7  ENSG00000164091 NA WDR82 WD repeat domain 82 80335 ENSG00000164091
8  ENSG00000099968 NA BCL2L13 BCL2-like 13 (apoptosis facilitator) 23786 ENSG00000099968
9  ENSG00000019995 NA ZRANB1 zinc finger, RAN-binding domain containing 1 54764 ENSG00000019995
10  ENSG00000171992 NA SYNPO synaptopodin 11346 ENSG00000171992
11  ENSG00000204843 NA DCTN1 dynactin 1 1639 ENSG00000204843
12  ENSG00000188549 NA C15orf52 chromosome 15 open reading frame 52 388115 ENSG00000188549


Database:Transcription Target       Name:hsa_TATAAA_V$TATA_01       ID:DB_ID:2456
C=1276; O=13; E=3.82; R=3.41; rawP=0.0001; adjP=0.0021
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000009307 NA CSDE1 cold shock domain containing E1, RNA-binding 7812 ENSG00000009307
2  ENSG00000205323 NA SARNP SAP domain containing ribonucleoprotein 84324 ENSG00000205323
3  ENSG00000163006 NA CCDC138 coiled-coil domain containing 138 165055 ENSG00000163006
4  ENSG00000197798 NA FAM118B family with sequence similarity 118, member B 79607 ENSG00000197798
5  ENSG00000138798 NA EGF epidermal growth factor 1950 ENSG00000138798
6  ENSG00000109685 NA WHSC1 Wolf-Hirschhorn syndrome candidate 1 7468 ENSG00000109685
7  ENSG00000109689 NA STIM2 stromal interaction molecule 2 57620 ENSG00000109689
8  ENSG00000164091 NA WDR82 WD repeat domain 82 80335 ENSG00000164091
9  ENSG00000019995 NA ZRANB1 zinc finger, RAN-binding domain containing 1 54764 ENSG00000019995
10  ENSG00000111540 NA RAB5B RAB5B, member RAS oncogene family 5869 ENSG00000111540
11  ENSG00000070182 NA SPTB spectrin, beta, erythrocytic 6710 ENSG00000070182
12  ENSG00000170242 NA USP47 ubiquitin specific peptidase 47 55031 ENSG00000170242
13  ENSG00000116497 NA S100PBP S100P binding protein 64766 ENSG00000116497


Database:Transcription Target       Name:hsa_V$STAT3_02       ID:DB_ID:2149
C=145; O=5; E=0.43; R=11.53; rawP=7.89e-05; adjP=0.0021
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116698 NA SMG7 smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) 9887 ENSG00000116698
2  ENSG00000006125 NA AP2B1 adaptor-related protein complex 2, beta 1 subunit 163 ENSG00000006125
3  ENSG00000165526 NA RPUSD4 RNA pseudouridylate synthase domain containing 4 84881 ENSG00000165526
4  ENSG00000035403 NA VCL vinculin 7414 ENSG00000035403
5  ENSG00000108424 NA KPNB1 karyopherin (importin) beta 1 3837 ENSG00000108424




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).